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Myxoid liposarcoma of hypopharynx- A diagnostic and management dilemma

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Case Report

Author Details : Ravneet R. Verma, Ravinder Verma

Volume : 4, Issue : 2, Year : 2018

Article Page : 57-62

https://doi.org/10.18231/2581-5229.2018.0016

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Abstract

Sarcomas are malignant neoplasms arising from connective tissue. They represent roughly 1% of all cancer cases reported. Overall, only 4-9% of all liposarcomas occur in head and neck region. A small uncommon group of soft tissue tumours are distinguished by their unique and consistant ability to produce an overwhelming abundance of myxoid ground substance along with the proliferating cells that constitute the tumour. Grossely all these neoplasms have a variable gelatinous quality. Because of the voluminous stroma most of these tumours have some findings that overlap with one another. Nonetheless each tumour has a composite set of morphologic, immunophenotypic, ultrastructural and genotypic features exclusive to itself.²⁶ (Wakely 1999) Hypopharyngeal localization is rarely described in the literature. Golledge et a1¹¹ (1995) reviewed the literature and reported 76 cases of liposarcoma of head and neck including 4 cases of their own. 38% of liposarcomas of head and neck involve larynx and /or pharynx.78% of these laryngeal pharyngeal cases arise in the supra glottic region and were well differentiated. Han et a1¹³ (2014) reported a total of 37 cases of Laryngeal liposarcoma reported in English or French literature. Although more common in other areas, it is rarely found in the aero-digestive tract. Liposarcomas typically occur in middle aged to older adults. These tumors are typically misdiagnosed secondary to their indolent, asymptomatic course and similarities in appearance to other benign lesions. An understanding of these lesions will help clinicians appropriately manage their patients.

Keywords: Liposarcoma, Well-differentiated liposarcoma, Hypopharynx.

How to cite : Verma R R, Verma R, Myxoid liposarcoma of hypopharynx- A diagnostic and management dilemma. IP Indian J Anat Surg Head Neck Brain 2018;4(2):57-62

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