IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain
Official Publication of Khyati Education And Research Foundation
Official Publication of Khyati Education And Research Foundation
Print ISSN: 2581-5210
Online ISSN: 2581-5229
CODEN : IIJAAL
IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain (IJASHNB) open access, peer-reviewed quarterly journal publishing since 2015 and is published under the Khyati Education and Research Foundation (KERF), is registered as a non-profit society (under the society registration act, 1860), Government of India with the vision of various accredited vocational courses in healthcare, education, paramedical, yoga, publication, teaching and research activity, with the aim of faster and better dissemination of knowledge, we will be publishing more...Original Article
Author Details :
Volume : 5, Issue : 1, Year : 2019
Article Page : 13-16
https://doi.org/10.18231/j.ijashnb.2019.002
Abstract
Introduction: Pyrethroids, organochlorines, organophosphates, and carbamates constitute important active ingredients of available mosquito repellents in the Indian market, in which pyrethroids are found very effective and safe. The natural compounds produced by plants can inter fere major metabolic pathways, thus causing death of the insects. The aim of present study was to know the effect of exposure and withdrawal of transfluthrin and herbal based mosquito vaporizers on spinal cord of male albino rats.
Materials and Methods: We have taken spinal cord of 26 well preserved male albino wistar rats and divided in to three groups.
Control Group: Six rats, notexposed to any mosquito repellents.
Experimental Group 1: 12 rats: divided in subgroup 1A, the pyrethroid Exposure group; and subgroup1B, the Pyrethroid withdrawal group.
Experimental Group 2: Eight rats: divided in subgroup 2A, the herbal Exposure group and 2B, the herbal withdrawal group.
Results: Spinal cord of pyrethroid vaporizer exposed group showed gross destruction in their histology than the herbal based mosquito vaporizer exposure group. Also, some of the normal histological features were recovered after withdrawal of chemicals and reversal was better in herbal based mosquito vaporizer.
Conclusion: Histological findings of present study suggests that pyrethroid (Transfluthrin) based mosquito repellents are harmful to the spinal cord. Herbal based mosquito repellent also showed damage though the severity was mild as compared to pyrethroid. Reversal changes were much better in herbal withdrawal group than the pyrethroid withdrawal group.
Keywords: Pyrethroid, Transfluthrin, Herbal, Mosquito repellent, Spinal cord, Withdrawal.
How to cite : Pankaj A K, Pandey M, Manik P, Rani A, Tomar S, Effect of exposure and withdrawal of pyethroid and herbal based mosquito vaporizers on histology of spinal cord of male wistar albino rats. IP Indian J Anat Surg Head Neck Brain 2019;5(1):13-16
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